Lipinski’s Rule of Five in Drug Design and Development

Lipinski’s Rule of Five, also known as Pfizer’s Rule of Five or simply the Rule of Five, is a valuable guideline in pharmaceutical research and drug development. It was developed by Christopher A. Lipinski in 1997 to assess the drug-likeness of chemical compounds, especially in terms of their suitability for oral administration in humans. This […]

Crispr/Cas9: A Game Changer Technique in Genetic Engineering and Biomedical Research

What is CRISPR/Cas9? CRISPR/Cas9 stands for Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated protein 9. It is a natural defense mechanism used by bacteria to protect themselves against viral infections. CRISPR/Cas9 is a revolutionary gene editing technology that has transformed the field of genetics and biomedical research. It enables researchers to manipulate and edit DNA sequences […]

The role of bioinformatics in advancing biotechnology

In the modern era of biotechnology, huge amounts of data are generated from various experiments, including sequencing genomes, analyzing gene expression, and characterizing proteins. The field of bioinformatics plays a crucial role in extracting useful insights from this data and using it to develop new biotechnological applications. In this article, we will explore the role of bioinformatics in advancing biotechnology, with examples from various sub-fields such as genomics, proteomics, and synthetic biology.

How to find out reverse strand and reverse complementary strand of DNA using Python

DNA (deoxyribonucleic acid) is made up of pentose Sugar, nitrogenous bases, and phosphate. DNA has a backbone of sugar and phosphate. As we all know DNA is a double helical structure (Watson & crick model) and both the strand of DNA are complementary to each other.
In this post we are going to learn how we can use the python program to find out the reverse strand and reverse complementary strand of DNA.

How to count amino acid in a protein sequence using Python program

In this article, we are going to learn how python can be useful in finding amino acid in a given protein sequence. Before reading this article you must know about FASTA format and single letter code for the amino acid. (Click here¬† FASTA format) Here, we will learn how can we find the total length […]

NCBI (National Center for Biotechnology Information)

NCBI stands for the National center for biotechnology information which is a composite database. We already have discussed the databases (Read here). The URL for NCBI is https://ncbi.nlm.nih.gov NCBI is an important database for biotechnology students and researchers. There are various tools available for the analysis of data. NCBI is inside connected with other databases […]

Importance of Bioinformatics

Bioinformatics is the branch of science in which we use computer tools and algorithms to analyze biological data. Bioinformatics has its importance in the management and collection of biological data. Bioinformatics is an integrated interdisciplinary field it includes various subjects such as math, chemistry, genomics, proteomics, etc. Bioinformatics includes research applications in genomics data and […]

How to find out the complementary strand of DNA using Python

What is a complementary strand? DNA (deoxyribonucleic acid) is made up of pentose Sugar, nitrogenous bases, and phosphate. DNA has a backbone of sugar and phosphate. As we all know DNA is a double helical structure (Watson & crick model) and both the strand of DNA are complementary of each other. So, what does it […]

Fasta format and Sequence comparison

What is fasta sequence? Fasta is a format used to represent nucleotide sequences or protein/peptide sequences. In the fasta format, the sequences are represented with their single letter code. E.g., for nucleotides A, T, G, C, U For proteins: A, M, D, etc. The fasta sequence of any nucleotide or peptide begins with a single […]

Biological databases

WHAT ARE DATABASES? Databases are electronic cabinets used in storing retrieving and data management. A biological database is a large organized body of persisted data coming from various laboratories. E.g. NCBI, Swissprot Types of databases Primary database: These databases are also known as archival databases. Generally, these databases are populated with experimental data such as […]