In the modern era of biotechnology, huge amounts of data are generated from various experiments, including sequencing genomes, analyzing gene expression, and characterizing proteins. The field of bioinformatics plays a crucial role in extracting useful insights from this data and using it to develop new biotechnological applications. In this article, we will explore the role of bioinformatics in advancing biotechnology, with examples from various sub-fields such as genomics, proteomics, and synthetic biology.